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Exosomes in solution

The future of skin rejuvenation is here

Advanced regenerative aesthetic solutions

  • Human-derived exosome therapies and skin rejuvenation solutions
  • Precision treatment delivery systems
  • Skin analysis technology

Introducing Yolo’s

Regenerative aesthetic solutions for modern clinical practice.

Yolo’s develops and supplies regenerative aesthetic products designed to support skin rejuvenation, tissue repair, and precision treatment planning. Our portfolio includes human adipose-derived and Cica-derived botanical exosome formulations, PDRN skin recovery solutions, advanced treatment delivery systems, and an AI-based skin analysis platform used by aesthetic professionals and medical clinics.

We focus on clinically relevant technologies that improve consistency, treatment efficiency, and patient satisfaction.

Through established manufacturing partnerships, we support private-label and ODM collaboration for qualified distributors and clinical brands.

Cross-Border Care Support

Clinic referrals for patients seeking treatment in Korea

Planning a visit to Korea for regenerative aesthetic treatment? Yolo’s can connect international patients with established clinics specializing in exosome and stem cell–based therapies and skin rejuvenation procedures.

Understanding Exosomes

Cell-derived messengers that support skin repair and regeneration

Exosomes are nanoscale extracellular vesicles released by cells that facilitate intercellular communication. They transport proteins, lipids, and signaling molecules that help regulate inflammation, support tissue repair, and promote skin regeneration.

Unlike live cells, exosomes are stable, cell-free messengers that can be stored and handled without the complexity associated with cellular therapies.

In aesthetic and regenerative applications, exosomes support:

  • Improved skin texture and elasticity
  • Reduction in visible signs of aging
  • Enhanced healing and recovery following procedures
  • Support for collagen production and tissue renewal

Regenerative Solution Categories

Yolo’s regenerative solutions include multiple biologically derived technologies designed to support different clinical needs:

Human-Derived
Utilizing CellExosome® PURE technology, these exosomes are harvested from high-quality stem cell culture media and ultra-purified using tangential flow filtration (TFF) to maintain vesicle integrity while removing non-exosomal proteins.

Plant-Derived
Featuring Exo-Cica®, these exosomes are derived from Centella asiatica. They combine regenerative signaling with natural anti-inflammatory properties, making them suitable for sensitive skin and barrier repair.

PDRN-Based
BelleGen solutions utilize PDRN derived from trout DNA. This bio-stimulator promotes DNA synthesis and works synergistically with exosome therapy to support elasticity, repair, and radiance.

Exosome Aesthetic Solutions

Yolo’s regenerative portfolio includes CellExosome PURE, Exoline, and BelleGen — clinically developed solutions supporting skin repair, barrier recovery, and tissue renewal across dermatology, hair restoration, and aesthetic treatments.

CellExosome PURE

Technology

Human Stem Cell Exosomes

CellExosome® PURE

Ultra-Purified Regenerative Exosome Formula

Ultra-purified using tangential flow filtration (TFF), PURE removes non-exosomal proteins while preserving vesicle integrity. Celtivation processing supports regenerative signaling for dermal repair and treatment recovery.

Purity

Protein Removal 99.9%

Activation

Celtivation Process

Exoline

Plant-Derived Exosome Booster

Powered by Exo-Cica®, Exoline utilizes Centella asiatica–derived exosomes to support skin barrier recovery, reduce inflammation, and improve overall skin resilience following aesthetic procedures.

Barrier Repair

Skin Recovery Support

Anti-Inflammatory

Sensitive Skin Friendly

Exoline

Technology

Exo-Cica Plant Exosome

Bellegen Skin Booster

Technology

PDRN + Nutrient Complex

BelleGen Skin Booster

PDRN-Based Dermal Regeneration Support

BelleGen utilizes PDRN derived from trout DNA to promote tissue repair, improve hydration, and support dermal regeneration. It is commonly used to enhance recovery and improve overall skin quality.

Tissue Repair

DNA Synthesis Support

Hydration & Renewal

Dermal Revitalization

Aesthetic Treatment Systems

Electroporation, RF, and precision injection technologies designed to improve absorption, tissue stimulation, and clinical outcomes.

Engineered for dermatology, aesthetic, and regenerative treatment protocols.

RF Combo Jector

Technology

Bipolar RF + Auto Injection

RF Combo Jector

Bipolar RF & Auto-Injection System

Combines bipolar radiofrequency stimulation with precision auto-injection to support dermal remodeling and controlled delivery of skin boosters and fillers.

Collagen Remodeling

RF energy supports dermal renewal and skin tightening.

Precision Delivery

Controlled depth and dosage support accurate dermal infusion.

Combo Jector

Precision Auto-Injection Mesotherapy System

A controlled micro-injection system designed to deliver active compounds into the dermis to support hydration, rejuvenation, and scalp care.

Targeted Dermal Delivery

Supports consistent distribution of active ingredients.

Patient Comfort

Suction-assisted skin adherence helps reduce discomfort.

Combo Jector

Technology

Auto Injection Mesotherapy

CellExosome PURE

Technology

Bipolar RF Microneedling

RM Star

Fractional RF Microneedling System

A bipolar RF microneedling platform designed to support collagen remodeling and improve skin texture.

Skin Remodeling

Fractional RF stimulation supports collagen regeneration.

Texture Improvement

Helps improve the appearance of scars, pores, and wrinkles.

Plajet Pro

Cold Plasma Therapy System

A plasma-based therapy device designed to support skin purification, microcirculation, and enhanced topical absorption.

Skin Purification & Soothing

Helps reduce acne-related bacteria and inflammation.

Enhanced Absorption

Supports improved penetration of topical solutions.

Exoline

Technology

Cold Atmospheric Plasma

Skin Analysis & Diagnostic Systems

Skin analysis supports personalized treatment protocols and enables objective monitoring of regenerative treatments such as exosome therapy.

A-ONE Smart

AI Skin Analysis & Diagnostic System

An advanced skin analysis platform that combines high-resolution imaging, multi-spectrum lighting, and AI-powered facial recognition to provide rapid, objective skin assessments for clinical consultation and treatment planning.

The A-ONE Smart performs a one-click full facial scan using a high-resolution camera and sensors, analyzing multiple skin parameters and generating visual reports for consultation and treatment tracking.

Comprehensive Skin Analysis

Measures pores, wrinkles, pigmentation, sebum, moisture, elasticity, skin tone, and temperature.

Multi-Spectrum Imaging

Normal, UV, and polarized light reveal both surface and subsurface skin conditions.

A One Smart

Technology

AI Facial Recognition + Multi-Spectrum Skin Imaging

Cosmetic OEM/ODM Solutions

Through strategic partnerships with leading Korean manufacturers, we deliver comprehensive OEM/ODM development for global brands. From concept formulation and packaging design to regulatory preparation and worldwide distribution, we turn innovative cosmetic ideas into market-ready products.

Modern Production Complex

Production Facility

High-Capacity Automation

Manufacturing Excellence

State-of-the-Art Korean Infrastructure

Working with highly specialized Korean production facilities, we support OEM/ODM manufacturing at every stage. Our partners combine precision engineering, rigorous quality control, and scalable production to ensure consistent results and reliable international supply.

  • Quality Foundations: ISO 22716–certified facilities supporting international regulatory compliance and global distribution.

  • Scalable Production: Flexible batch capacity supported by HOMO-MIXER and DISPER-MIXER processing technologies.

  • Formulation Innovation: Access to patented natural mushroom–derived actives for functional differentiation and product storytelling.